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Search Results (19)
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Stem cell therapy for Alport syndrome: the hope beyond the hype.
Academic Article
Why?
Borza, Dorin-Bogdan
Person
Why?
A glycine substitution in the collagenous domain of Col4a3 in mice recapitulates late onset Alport syndrome.
Academic Article
Why?
Editorial: Collagen IV nephropathies: Alport syndrome and beyond.
Academic Article
Why?
Nephritis, Hereditary
Concept
Why?
A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice.
Academic Article
Why?
Alport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: protection by quinary crosslinks locking cryptic a3(IV) collagen autoepitopes in vivo.
Academic Article
Why?
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Academic Article
Why?
Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis.
Academic Article
Why?
Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy.
Academic Article
Why?
Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.
Academic Article
Why?
Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis.
Academic Article
Why?
Quaternary epitopes of a345(IV) collagen initiate Alport post-transplant anti-GBM nephritis.
Academic Article
Why?
The alloantigenic sites of alpha3alpha4alpha5(IV) collagen: pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the alpha5NC1 domain.
Academic Article
Why?
Cellular origins of type IV collagen networks in developing glomeruli.
Academic Article
Why?
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